Possible Mechanism of Signaling for Permeability Enhancement in Intestinal Mucosa.

A new test for canine intestinal mucosa permeability

Results The least squares means of mannitol proportion (excreted/ingested ± SE) was 15.6 % (± 2.0), 11.0 % (± 2.1) and 5.5 % (± 2.1) for urine sampled 2, 4 and 6 h after ingestion (p<0.0001). Hence, the majority of mannitol absorption and secretion representing upper gastrointestinal leakage was completed by 4 h. Riboflavin followed a similar temporal profile, defining 4 h as a cutoff for upper...

A Possible Enhancement Mechanism of Nuclear Fusion

An enhancing mechanism of nuclear fusions is presented, most part of which is within the framework of the traditional theories. In this mechanism, electron currents play an important role, which are induced by an externally applied field or counterstreams of free electrons which naturally exist inside, surface and outside of bulk metals. At places of electron currents, the electric potential be...

Intestinal permeability measurements: general aspects and possible pitfalls.

INTRODUCTION Disturbances of the gut barrier function have been related to a variety of diseases, including intestinal and extra-intestinal diseases. The intestinal permeability tests are considered useful tools for evaluating disease severity and to follow-up patients after a therapeutic intervention and indirectly assess barrier function. OBJECTIVE The aims of this review were to highlight ...

The Study of Gastric Mucosa for Possible Bacterial Causative Agent of Crohn’s Disease

Cellular Mechanism of Intestinal Permeability Alterations Produced by Chelation Depletion

The absorption of phenolsulfonphthalein (phenol red) was used as a measure in vivo of intestinal permeability in anesthetized rats. A chelating agent, sodium ethylenediaminetetraacetate (NaEDTA), placed in the lumen evoked a fivefold increase in membrane permeability; at the same time the mucosal content of magnesium and calcium decreased significantly. Making either magnesium or calcium availa...